Talk to your doctor about the risks of taking levofloxacin. If you have myasthenia gravis and your doctor tells you that you should take levofloxacin, call your doctor immediately if you experience muscle weakness or difficulty breathing during your treatment. Your doctor may tell you not to take levofloxacin. Tell your doctor if you have myasthenia gravis. Taking levofloxacin may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death. If you experience any of the following symptoms, stop taking levofloxacin and call your doctor immediately: seizures tremors dizziness lightheadedness headaches that won't go away (with or without blurred vision) difficulty falling asleep or staying asleep nightmares not trusting others or feeling that others want to hurt you hallucinations (seeing things or hearing voices that do not exist) thoughts or actions towards hurting or killing yourself feeling restless, anxious, nervous, depressed, memory problems, or confused, or other changes in your mood or behavior. Tell your doctor if you have or have ever had seizures, epilepsy, cerebral arteriosclerosis (narrowing of blood vessels in or near the brain that can lead to stroke or ministroke), stroke, changed brain structure, or kidney disease. This can occur after the first dose of levofloxacin. Taking levofloxacin may affect your brain or nervous system and cause serious side effects. If you experience any of the following symptoms, stop taking levofloxacin and call your doctor immediately: numbness, tingling, pain, burning, or weakness in the arms or legs or a change in your ability to feel light touch, vibrations, pain, heat, or cold. Tell your doctor if you have ever had peripheral neuropathy (a type of nerve damage that causes tingling, numbness, and pain in the hands and feet). This damage may occur soon after you begin taking levofloxacin. Taking levofloxacin may cause changes in sensation and nerve damage that may not go away even after you stop taking levofloxacin. If you experience any of the following symptoms of tendon rupture, stop taking levofloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or bear weight on an affected area. If you experience any of the following symptoms of tendinitis, stop taking levofloxacin, rest, and call your doctor immediately: pain, swelling, tenderness, stiffness, or difficulty in moving a muscle. Tell your doctor and pharmacist if you are taking oral or injectable steroids such as dexamethasone, methylprednisolone (Medrol), or prednisone (Rayos). Tell your doctor if you have or have ever had a kidney, heart, or lung transplant kidney disease a joint or tendon disorder such as rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function) or if you participate in regular physical activity. Tendinitis or tendon rupture may happen to people of any age, but the risk is highest in people over 60 years of age. These problems may affect tendons in your shoulder, your hand, the back of your ankle, or in other parts of your body. Taking levofloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward.
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